TIP60 inhibits metastasis by ablating DNMT1−SNAIL2-driven epithelial-mesenchymal transition program
نویسندگان
چکیده
منابع مشابه
Targeting ROR1 inhibits epithelial-mesenchymal transition and metastasis.
Metastasis is responsible for 90% of cancer-related deaths. Strategies are needed that can inhibit the capacity of cancer cells to migrate across the anatomic barriers and colonize distant organs. Here, we show an association between metastasis and expression of a type I receptor tyrosine kinase-like orphan receptor, ROR1, which is expressed during embryogenesis and by various cancers, but not ...
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ژورنال
عنوان ژورنال: Journal of Molecular Cell Biology
سال: 2016
ISSN: 1674-2788,1759-4685
DOI: 10.1093/jmcb/mjw038